瑞替加滨溶液降解动力学的研究Degradation kinetics of retigabine in solution
王玉霞,张林林
摘要(Abstract):
研究了瑞替加滨在不同温度和pH值下的降解动力学,采用反相HPLC的方法对降解后的溶液进行测定。结果表明,瑞替加滨在不同温度和不同pH值下的降解都遵循一级降解动力学,瑞替加滨的降解速率受温度和pH的影响显著,在低温、pH值为3时相对稳定。
关键词(KeyWords): 瑞替加滨;降解动力学;温度;pH
基金项目(Foundation):
作者(Author): 王玉霞,张林林
DOI: 10.16581/j.cnki.issn1671-3206.2013.09.025
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